17. CHEM352 Analytical Chemistry
UNIT I (Tools and Data Handling) Balances, burettes, volumetric flasks, pipettes, calibration of tools, sampling. Errors and Statistics: significant figures, rounding off, accuracy and precision, determinate and indeterminate errors, standard deviation, propagation of errors, confidence limit, test of significance, rejection of a result.
UNIT II (Separation Techniques) Solvent Extraction: distribution Coefficient, distribution ratio, solvent extraction of metals, multiple batch extraction, counter current distribution. - Chromatographic Techniques: classification, theory of chromatographic separation, distribution coefficient, retention, sorption, efficiency and resolution. - Column, ion exchange, paper, TLC & HPTLC: techniques and application. - Gas Chromatography: retention time or volume, capacity ratio, partition coefficient, theoretical plate and number, separation efficiency and resolution, instrumentation and application.
UNIT III (Spectroscopic Techniques) Electromagnetic radiation, absorption, and emission of radiation – instrumentation: sources, monochromators, detectors. - Flame spectrometry: flame emission, AAS, ICP, instrumentation and application. - Absorption spectrometry: UV-VIS, IR, instrumentation, techniques and applications.
UNIT – IV Thermal and Radiochemical Techniques: Thermogravimetry: instrumentation and techniques, TGA curves, DTA and DSC, applications. Radiochemical methods: decay reactions, growth of radioactivity, radiation detectors, tracer techniques.
UNIT V (Electroanalytical Techniques) Electrogravimetry, coulometry, voltam- metry, polarography, conductometry, instrumentation, techniques and application.
Textbook: D. C. Harris,
Quantitative Chemical Analysis, 4 th Ed., W. H. Freeman, 1995
G. D.Christian & J. E. O’Reily, Instrumental Analysis, 2 nd Ed., Allyn & Balon, 1986.